Addiction
☆ Watchdysfunction · Score (benefits ÷ risk): Unrated (0 ratings) — needs ≥ 3 ratings
Addiction is a chronic, relapsing dysfunction of the brain's reward, motivation, and memory circuitry — compulsive substance use or behavior that continues despite harmful consequences. It centers on dysregulated dopamine signaling in the mesolimbic reward pathway, with adaptations in glutamate and GABA systems.
Neurotransmitters
Related stimuli
Research (5)
- Gut microbiota modulates neurotransmitter and gut-brain signaling Wang et al. (2024)
- The Formation and Function of the VTA Dopamine System Duan et al. (2024)
- Alpha5 nicotine acetylcholine receptor subunit promotes intrahepatic cholangiocarcinoma metastasis Wang et al. (2024)
- Modulating the Neuromodulators: Dopamine, Serotonin, and the Endocannabinoid System Peters et al. (2021)
- The debate over dopamine's role in reward: the case for incentive salience Berridge (2007)
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