Benzodiazepines
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Benzodiazepines (e.g., diazepam, alprazolam, lorazepam, clonazepam) are sedative-hypnotic drugs that enhance the inhibitory neurotransmitter GABA, producing anxiolytic, sedative, hypnotic, and muscle-relaxant effects. They are effective short-term but carry a high risk of tolerance and dependence.
Too much may be associated with
Sedation, cognitive and memory impairment, falls, and — especially when combined with opioids or alcohol — dangerous respiratory depression. Regular use leads to tolerance and physical dependence, with a protracted and potentially life-threatening withdrawal syndrome (seizures, severe anxiety) that requires medically supervised tapering.
Informational only — not medical advice.
Neurotransmitters
Related stimuli
Research (6)
- GABAergic mechanisms in alcohol dependence Uusi-Oukari et al. (2024)
- Shared structural mechanisms of general anaesthetics and benzodiazepines Teng et al. (2020)
- Structure of a human synaptic GABA(A) receptor Teng et al. (2018)
- Ethanol and GABA Kulonen (1983)
- Dopamine and antianxiety activity Taylor et al. (1982)
- Pharmacology of GABA Meldrum (1982)
Recovery resources
Help for benzodiazepines use and recovery. Not an endorsement or medical advice — see all recovery resources.
Narcotics Anonymous (NA)
A global 12-step fellowship for people recovering from addiction to any drug.
SMART Recovery
A secular, science-based recovery program using cognitive-behavioral tools for any addictive behavior.
Community
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