SAM-e (S-Adenosylmethionine)
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S-Adenosylmethionine (SAM-e) is a naturally occurring compound and universal methyl donor central to the synthesis of the monoamine neurotransmitters dopamine, serotonin, and norepinephrine. It is taken as a supplement for depression, osteoarthritis, and liver health.
Neurotransmitters
Books (3)
SAMe (S-Adenosylmethionine): The European Arthritis and Depression Breakthrough
The SAM-e Handbook: The Fast, Natural Way to Overcome Depression, Relieve the Pain of Arthritis, Alleviate the Discomfort of Fibromyalgia, and Boost Your Energy
The SAM-e Solution: The Essential Guide to the Revolutionary Antidepression Supplement
Research (9)
- S-adenosyl-l-methionine antidepressant-like effects involve activation of 5-HT(1A) receptors Sales et al. (2023)
- Possible SAMe-induced mania Abeysundera et al. (2018)
- S-Adenosyl Methionine in the Therapy of Depression and Other Psychiatric Disorders Karas (2016)
- [Other therapeutic strategies] Saba et al. (2016)
- [S-adenosyl L-methionine in CNS diseases] Krzystanek et al. (2011)
- S-Adenosylmethionine and methylation Chiang et al. (1996)
- The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders Reynolds et al. (1994)
- Neuropharmacology of S-adenosyl-L-methionine Baldessarini (1987)
- S-adenosylmethionine and affective disorder Carney et al. (1987)
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