Valerian root
Valerian is a traditional herbal sedative used for insomnia and anxiety, thought to act partly on GABA. Trial results are inconsistent, with some suggesting modest improvement in sleep quality and others showing no clear benefit over placebo. It is generally well tolerated for short-term use.
Too little may be associated with
Less sleep support.
Too much may be associated with
Grogginess, headache; sedative interactions.
Informational only — not medical advice.
Neurotransmitters
Related
Research (5)
- An Alternative Cause of Encephalopathy: Valerian Root Overdose Freitas et al. (2021) Full text ↗ PubMed ↗
- De novo synthesis of the sedative valerenic acid in Saccharomyces cerevisiae Wong et al. (2018) Full text ↗ PubMed ↗
- GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts Benke et al. (2009) Full text ↗ PubMed ↗
- Analysis of responses to valerian root extract in the feline pulmonary vascular bed Fields et al. (2003) Full text ↗ PubMed ↗
- Synaptosomal GABA release as influenced by valerian root extract--involvement of the GABA carrier Santos et al. (1994) PubMed ↗
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